Host-guest interactions for extracting antibiotics with a γ-cyclodextrin poly(glycidyl-co-ethylene dimethacrylate) hybrid sorbent

Belenguer-Sapiña, C. and Pellicer-Castell, E. and Pottanam Chali, S. and Ravoo, B. J. and Amorós, P. and Simó-Alfonso, E. F. and Mauri-Aucejo, A. R. (2021) Host-guest interactions for extracting antibiotics with a γ-cyclodextrin poly(glycidyl-co-ethylene dimethacrylate) hybrid sorbent. [Publications (Pre-joining)]

Text - Published Version Restricted to Registered users only Download (3MB) | Request a copy

Abstract

A procedure for the solid-phase extraction of antibiotics (enoxacin, ofloxacin, norfloxacin, ciprofloxacin, and sparfloxacin) in water has been developed. The sorbent used is based on a poly(glycidyl-co-ethylene dimethacrylate) network, whose previously modified surface has been functionalized with γ-cyclodextrin through a clickchemistry reaction. The architecture of the material has been characterized by thermogravimetric analysis, N2 adsorption-desorption, Raman spectroscopy, confocal microscopy, and scanning electron microscopy, showing good capability to be used as a filler for extraction cartridges. The optimization of the extraction methodology shows good intra-day and inter-day repeatability of the extraction procedure, with coefficients of variation between 2.5 and 5.1% and the possibility of reusing the material at least five times. The detection limits of the method have been established at the μg L− 1 level, confirming the possibility of quantifying trace levels. To end, real groundwater samples have been analyzed and the results are comparable with those obtained with a reference method. The proposed material can be used for assessing the presence of antibiotics in aqueous environments through an extraction procedure taking advantage of the presence of γ-cyclodextrin on its structure.

Item Type:	Publications (Pre-joining)
Authors:	Belenguer-Sapiña, C. and Pellicer-Castell, E. and Pottanam Chali, S. and Ravoo, B. J. and Amorós, P. and Simó-Alfonso, E. F. and Mauri-Aucejo, A. R.
Document Language:	Language English
Uncontrolled Keywords:	GMA-co-EDMA, Surface modification, Cyclodextrin, Groundwater, Fluoroquinolones
Subjects:	Natural Sciences
Divisions:	Azim Premji University - Bengaluru > School of Arts and Sciences
Full Text Status:	Restricted
URI:	http://publications.azimpremjiuniversity.edu.in/id/eprint/6652
Publisher URL:	https://doi.org/https://doi.org/10.1016/j.talanta....

Actions (login required)

View Item